Genes will help to create pain medications

Why some people experience less pain? This stability has a genetic origin, which eliminates some of the lucky ones from having to swallow the medication after surgery.

Sensitivity to pain or pain threshold is a very important topic for most of us. All of us at some period of life are faced with pain, whether they involve heads, teeth, or other body parts. And many came up with the idea of how we would be happy if experienced less pain without taking medications. Note that pain is the single most common symptom that people seek medical help and medicines.In normal circumstances, pain signals indicative of any such injury or damage is a natural response to protect our body. When people get better, the pain usually subsides, medication overturned.

However, practice shows that we all experience pain differently. For some, even minor pain symptoms become a real pain, someone may suffer from severe pain and not take medication. If science figured out that it helps in some people to reduce sensitivity to pain, would bring us closer to the development of new anesthetic drugs non-narcotic based, i.e., do not cause drug dependence that are so needed by many patients.

Thanks to the sequencing of the human genome we have learned a lot about the number and location of genes that make up our DNA. Millions of tiny variations within these genes have also been identified, some of which affect sensitivity to pain. In particular it is proved that variations of the gene SCN9A, not only provoke insensitivity to pain, but also trigger several serious conditions that are accompanied by extreme pain: primary erythromelalgia and paroxysmal pain occurs. These hereditary pain conditions are extremely rare, however, the industry of drugs based on the genome develops, and any research in this matter can play a key role in the creation of the most powerful painkillers, which will enable humanity to cope with one of the most common and unpleasant symptoms. (READ MORE)